Ultrasonic Debridement with Stem Cell Therapy of Suspensory Branch Desmitis in an Equine Patient

Abstract

Ultrasonic debridement as a treatment for tendinopathy and desmitis is a relatively new approach in orthopedic surgery. Previously only used in limited cases, this procedure shows promise for treating ligament-bone and tendon-bone interface injuries. We present a case study of a 2-year-old thoroughbred male horse, unable to train due to recalcitrant symptoms after extensive conservative management of suspensory branch desmitis (SBD). He was then treated with ultrasonic debridement and concurrent manubrial stem cell autograft injection, to treat the ultrasound visualized lesion. Post-surgically the patient recovered quickly, began training within 6 weeks and went onto win several races. Repeat ultrasound imaging reveals a complete restoration of the internal fiber architecture of the ligament. With a 3 year follow-up, there has been consistent training and race performance with no re-injury. This study is the first to document the successful outcome of ultrasonic debridement with concurrent stem cell injection in the treatment of equine desmitis.

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Prevention of Negative Impact of Pesticides and Other Toxic Substances on Reproductive Function of Animals

 Introduction

In acutely facing the problem of remote consequences of influence on an organism of chemical substances, impact on reproductive function is important. In recent years, in farms and private farms specializing in the cultivation of cattle and small cattle, as well as rabbits, there are violations of reproductive function, manifested in infertility and spontaneous abortions, pre - and postimplantation developmental delay, physiological and behavioral changes in the offspring, malformations and transplacental effects, and often their etiology remains unclear. Our long-term production and experimental studies allow us to conclude that one of the leading factors in the development of these violations is the unfavorable environmental situation in many regions of Uzbekistan as a result of various anthropogenic influences, including: the significant use of chemicals to protect plants and animals from pests and diseases, as well as other toxic substances. Currently, the most widespread as a means of protection of plants and animals from various pests have synthetic pyrethroids (cypermethrin, esfenvalerate, karate) and organophosphorus pesticides (basudin, aktellik, etapas, location) [1-3].

 

The use of these drugs helps to increase the yield of food and industrial crops, reduce production costs, protects productive animals from ecto - and endoparasites – carriers of various infections and invasions. However, their irrational use often causes environmental pollution (soil, water sources, feed) and causes poisoning, other negative consequences and, in particular, violations of the reproductive function of animals. Among other toxic substances that adversely affect the reproductive function of animals, gossypol cotton feed deserves some attention.

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Prevention and Correction of Immunodeficiency States of Animals, Chemical Etiology

 Introduction

In recent years, in farm and private livestock farms in Uzbekistan there has been a decrease in the resistance of animals and, especially, young animals to various bacterial and viral infections. Often there is a decrease and a complete lack of protective action of known vaccines and serums, which causes serious economic damage to livestock. One of the leading factors of this pathology is the unfavorable ecological situation which has developed in many regions of the Republic owing to various anthropogenic influences, including: application of pesticides and other toxic xenobiotics and also emissions of industrial productions.

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